Acute liver failure

Acute liver failure


usually no existing few days to people who do not have liver disease, or in a few weeks – acute liver failure is the loss of rapidly occurring liver function. Acute liver failure, chronic liver failure to develop more slowly, is more less common.

In addition, acute liver failure, which is known as fulminate liver failure, can cause serious complications, such as an increase in the pressure of excessive bleeding and in the brain. This is a medical emergency requiring hospitalization.

Depending on the cause, acute liver failure can sometimes be reversed in the process. In many situations, however, liver transplantation may be the only treatment.



It will include signs and symptoms of acute liver failure

  • Yellowing of the skin and eye (jaundice)
  • Pain of your right lower abdomen
  • Abdominal distension
  • nausea
  • vomiting
  • General sense is poor physical condition of feeling (malaise)
  • Disorientation and confusion
  • sleepiness

When you will see a doctor

Acute liver failure, can be developed immediately to healthy people otherwise, and it is life-threatening. If you or you suddenly know, someone to develop a yellowing of the eyes and skin, upper abdominal tenderness; or mental state, abnormal changes in personality and behavior, please consult a doctor immediately.



Liver cells is significantly damaged, acute liver failure occurs when you have not been able to no longer function. As possible causes,

  • Acetaminophen overdose:

    Taking too many of acetaminophen (Tylenol, others) is the most common cause of acute liver failure in the United States. Acute liver failure will have one after the very large doses, or high likelihood that after the acetaminophen than every day for a few days recommended dose.

    You are, someone you and you know it, if you think that is taking the overdose of acetaminophen, please consult a doctor as soon as possible. Do not wait for signs of liver failure.

  • Prescription drugs:


Antibiotics, some of the prescription drugs, including non-steroidal anti-inflammatory drugs and anticonvulsants, can cause acute liver failure.

  • Herbal supplements:

Hippopotamus, ephedra, herbal medicines and supplements, such as skullcap and Penny Royal, has been linked to acute liver failure.

  • Hepatitis and other viral:

Hepatitis A, B hepatitis and hepatitis E, can cause acute liver failure. Other viruses that can cause acute liver failure, Epstein Barr Virus, cytomegalovirus and herpes simplex virus.

  • toxin:

Potential toxin that causes acute liver failure will contain the occasional mistake is poisonous wild mushroom Amanita phalloides for edible species.

  • Autoimmune disease:

Your immune system, cause inflammation and injury, disease attacks the liver cells – liver failure, can be caused by autoimmune hepatitis.

  • Diseases of the veins in the liver:

Vascular disease, such as such bad Chiari syndrome, leading to acute liver failure, can cause blockage in the vein of the liver.

  • Metabolic disease:

Rare metabolic diseases such as acute fatty liver of pregnancy such a Wilson’s disease, causes a rare acute liver failure.

  • Cancer:

Cancer either to start or spread to your liver is there is a possibility that your liver to fail.



Acute liver failure often contain, it can cause complications

  • Excess fluid in the brain (cerebral edema):

It is possible to displace the outside of the brain tissue of normal occupancy space (hernia), excess fluid causes pressure to build in your brain. Brain edema is also, you can deprive your brain of oxygen.

  • Bleeding disorder or bleeding:

Failed liver, it will not be able to produce a sufficient amount of clotting factor that helps the blood to clot. People with acute liver failure, in many cases, and bleeding onset from the gastrointestinal tract. Control of bleeding is obtained is difficult.

  • Infection:

People with acute liver failure, especially in the respiratory and urinary tract in the blood, there is a high risk of developing a variety of infection.

  • kidney failure:

Renal failure, in many cases, especially in the case of acetaminophen overdose, in both of the damages your liver and your kidneys, to occur after the liver failure.

Testing and diagnosis:

Test and procedures used to diagnose acute liver failure include the:

  • Blood test:

Blood tests, your liver is, it will determine how well is functioning can include a test of measuring prothrombin time the time it takes for your blood to clot. In acute liver failure, blood is not clotting as need it soon

  • Image inspection:

For your doctor to evaluate your liver, you can recommend the image tests such as ultrasound. Image inspection, you can and can show the damage of the liver is your doctor to determine the cause of your liver problems.

  • Examination of liver tissue:

The doctor will be able to recommend a procedure to remove a small piece of liver tissue (liver biopsy). Test of liver tissue, it may help you understand why your doctor that your liver has failed.

People with acute liver failure, because they are exposed to the risk of bleeding at the time of biopsy, the doctor will be able to perform through the jugular vein liver biopsy. Through a small incision on the right side of your neck, your doctor through your mind, in the veins draining from your liver, it passes a thin tube (catheter) in a large vein in your neck. The doctor then, the needle is inserted into the bottom through a catheter, to get a sample of liver tissue.


Treatment and medicine:

People with acute liver failure, if many cases possible, facilities capable of performing liver transplant as required, – and hospital have been treated in intensive care. To control the complications, given the time of your liver to heal, your doctor, but you might try to treat liver damage itself, in many cases, it will include treatment

The treatment of acute liver failure:

This may also include the treatment of acute liver failure

  • Drugs to reverse the poisoning:

Acute liver failure caused by acetaminophen overdose or mushroom poisoning, it can the effect of the toxin on the contrary, has been treated with an agent capable of reducing liver damage.

  • Liver transplant:

If it is not possible to acute liver failure Conversely, only treatment is may be a liver transplant. During the liver transplant, the surgeon removes the received liver your damage, and replace it with the healthy liver from a donor.

Treatment of complications:

The doctor will control the symptoms that you are experiencing the symptoms, will continue to try to prevent complications due to acute liver failure. It may contain this care.

  • Relief pressure caused by excess fluid in the brain:

    It can increase the pressure on your brain, cerebral edema caused by acute hepatic failure. Medicine can reduce the accumulation of fluid in your brain.

  • Screening of infectious diseases:

Your medical team to take a regular sample of your blood and urine tests for infection. Your doctor if you suspect that you are infected, you will receive a medicine for the treatment of infectious diseases.

  • To prevent severe bleeding:

Your doctor will be able to give the medicine in order to reduce the risk of your bleeding. If you’ve lost a lot of blood, your doctor can perform tests to find the cause of the loss of blood, you might need a blood transfusion.


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